{"id":8,"date":"2009-05-31T22:08:08","date_gmt":"2009-06-01T02:08:08","guid":{"rendered":"http:\/\/www.petertbuckley.com\/?page_id=8"},"modified":"2025-05-19T02:40:18","modified_gmt":"2025-05-19T06:40:18","slug":"scientific-publications","status":"publish","type":"page","link":"http:\/\/www.petertbuckley.com\/?page_id=8","title":{"rendered":"Scientific Publications"},"content":{"rendered":"\n<div class=\"wp-block-columns alignfull is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\">\n<h1 class=\"wp-block-heading\">Key<strong> Peer Reviewed Journal Articles<\/strong><\/h1>\n\n\n\n<div class=\"docsum-wrap\">\n<p><a class=\"docsum-title\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37098341\/\" data-ga-category=\"result_click\" data-ga-action=\"1\" data-ga-label=\"37098341\" data-full-article-url=\"from_term=peter+t+buckley&amp;from_pos=1\" data-article-id=\"37098341\">Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections.<\/a><span class=\"docsum-authors full-authors\"><b>&nbsp;Buckley PT<\/b>, Chan R, Fernandez J, Luo J, Lacey KA, DuMont AL, O&#8217;Malley A, Brezski RJ, Zheng S, Malia T, Whitaker B, Zwolak A, Payne A, Clark D, Sigg M, Lacy ER, Kornilova A, Kwok D, McCarthy S, Wu B, Morrow B, Nemeth-Seay J, Petley T, Wu S, Strohl WR, Lynch AS, Torres VJ.<\/span><span class=\"docsum-journal-citation full-journal-citation\">Cell Host Microbe. 2023 May 10;31(5):751-765.e11. doi: 10.1016\/j.chom.2023.04.004. Epub 2023 Apr 24.<\/span><span class=\"citation-part\"><span class=\"citation-part\">PMID: <span class=\"docsum-pmid\">37098341<\/span><\/span><\/span><\/p>\n<p><a class=\"docsum-title\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21382548\/\" data-ga-category=\"result_click\" data-ga-action=\"10\" data-ga-label=\"21382548\" data-full-article-url=\"from_term=peter+t+buckley&amp;from_pos=10\" data-article-id=\"21382548\">Cytoplasmic intron sequence-retaining transcripts can be dendritically targeted via ID element retrotransposons.<\/a><span class=\"docsum-authors full-authors\"><b>&nbsp;Buckley PT<\/b>, Lee MT, Sul JY, Miyashiro KY, Bell TJ, Fisher SA, Kim J, Eberwine J.<\/span><span class=\"docsum-journal-citation full-journal-citation\">Neuron. 2011 Mar 10;69(5):877-84. doi: 10.1016\/j.neuron.2011.02.028.<\/span><span class=\"citation-part\"><span class=\"citation-part\">PMID: <span class=\"docsum-pmid\">21382548<\/span><\/span><\/span><\/p>\n<p><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/10462554?ordinalpos=13&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">Identification, molecular cloning, expression, and characterization of a cysteinyl leukotriene receptor.<\/a> Sarau HM, Ames RS, Chambers J, Ellis C, Elshourbagy N, Foley JJ, Schmidt DB, Muccitelli RM, Jenkins O, Murdock PR, Herrity NC, Halsey W, Sathe G, Muir AI, Nuthulaganti P, Dytko GM, Buckley PT, Wilson S, Bergsma DJ, Hay DW. Mol Pharmacol. 1999 Sep;56(3):657-63.<\/p>\n<\/div>\n\n\n\n<h1 class=\"wp-block-heading\"><strong>Book Chapters<\/strong><\/h1>\n\n\n\n<p>&#8220;<a href=\"http:\/\/www.sciencedirect.com\/science?_ob=GatewayURL&amp;_method=citationSearch&amp;_uoikey=B98GH-4TVBCX5-NK&amp;_origin=SDEMFRHTML&amp;_version=1&amp;md5=c6bdec37f2b63140ad8802e0efa043e8\" target=\"_blank\" rel=\"noopener\">RNA Binding Protein Methods<\/a>&#8221; P.T. Buckley, J. Eberwine. &nbsp;2009, In: Encyclopedia of Neuroscience (pp. 383-388), Larry R. Squire, Ed. Academic Press, Oxford.<\/p>\n\n\n\n<p>&#8220;<a href=\"http:\/\/www3.interscience.wiley.com\/cgi-bin\/summary\/120756442\/SUMMARY\" target=\"_blank\" rel=\"noopener\">Genomics Approaches to the Study of Neurodegeneration<\/a>&#8221; J.&nbsp;Jochems, P. Buckley, and J. Eberwine. 2008, In: Neural Degeneration and Repair (pp. 167-179), Hans Werner M\u00fcller, Ed. Wiley-VCH Verlag GmbH &amp; Co. KGaA.<\/p>\n\n\n\n<h1 class=\"wp-block-heading\"><strong>Additional Peer Reviewed Journal Articles<\/strong><\/h1>\n\n\n\n<div class=\"docsum-wrap\">\n<p><a class=\"docsum-title\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39537195\/\" data-ga-category=\"result_click\" data-ga-action=\"2\" data-ga-label=\"39537195\" data-full-article-url=\"from_term=peter+t+buckley&amp;from_pos=2\" data-article-id=\"39537195\">A single upstream mutation of whiB7 underlies amikacin and clarithromycin resistance in Mycobacterium abscessus.<\/a><\/p>\n<p><span class=\"docsum-authors full-authors\">De Boeck N, Villellas C, Crespo-Yuste E, Gonzalo-Asensio J, <b>Buckley PT<\/b>, Thys K, Vuong C, Lounis N, Verstraeten N, Michiels J.<\/span><span class=\"docsum-journal-citation full-journal-citation\">J Appl Microbiol. 2024 Nov 4;135(11):lxae286. doi: 10.1093\/jambio\/lxae286.<\/span><span class=\"citation-part\">PMID: <span class=\"docsum-pmid\">39537195<\/span><\/span><\/p>\n<div class=\"docsum-citation full-citation\"><a class=\"docsum-title\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35213810\/\" data-ga-category=\"result_click\" data-ga-action=\"7\" data-ga-label=\"35213810\" data-full-article-url=\"from_term=peter+t+buckley&amp;from_pos=7\" data-article-id=\"35213810\"><em>Staphylococcus aureus<\/em> in Non-Cystic Fibrosis Bronchiectasis: Prevalence and Genomic Basis of High Inoculum \u03b2-Lactam Resistance. <\/a><span class=\"docsum-authors full-authors\">Mossman AK, Svishchuk J, Waddell BJM, Izydorczyk CS, <b>Buckley PT<\/b>, Hilliard JJ, Al-Ghalith G, Zheng L, Lynch AS, Mody CH, Lisboa LF, Gregson DB, Parkins MD.<\/span><span class=\"docsum-journal-citation full-journal-citation\">Ann Am Thorac Soc. 2022 Aug;19(8):1285-1293. doi: 10.1513\/AnnalsATS.202108-965OC.<\/span><span class=\"citation-part\">PMID: <span class=\"docsum-pmid\">35213810<\/span><\/span><\/div>\n<div class=\"docsum-citation full-citation\"><a class=\"docsum-title\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30651319\/\" data-ga-category=\"result_click\" data-ga-action=\"8\" data-ga-label=\"30651319\" data-full-article-url=\"from_term=peter+t+buckley&amp;from_pos=8\" data-article-id=\"30651319\">Identification of biologic agents to neutralize the bicomponent leukocidins of <em>Staphylococcus aureus<\/em>. <\/a><span class=\"docsum-authors full-authors\">Chan R, <b>Buckley PT<\/b>, O&#8217;Malley A, Sause WE, Alonzo F 3rd, Lubkin A, Boguslawski KM, Payne A, Fernandez J, Strohl WR, Whitaker B, Lynch AS, Torres VJ.<\/span><span class=\"docsum-journal-citation full-journal-citation\">Sci Transl Med. 2019 Jan 16;11(475):eaat0882. doi: 10.1126\/scitranslmed.aat0882.<\/span><span class=\"citation-part\">PMID: <span class=\"docsum-pmid\">30651319<\/span><\/span><\/div>\n<div class=\"docsum-citation full-citation\"><a class=\"docsum-title\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28924032\/\" data-ga-category=\"result_click\" data-ga-action=\"11\" data-ga-label=\"28924032\" data-full-article-url=\"from_term=peter+t+buckley&amp;from_page=2&amp;from_pos=1\" data-article-id=\"28924032\">Staphylococcus aureus Strain Newman D2C Contains Mutations in Major Regulatory Pathways That Cripple Its Pathogenesis. <\/a><span class=\"docsum-authors full-authors\">Sause WE, Copin R, O&#8217;Malley A, Chan R, Morrow BJ, <b>Buckley PT<\/b>, Fernandez J, Lynch AS, Shopsin B, Torres VJ.<\/span><span class=\"docsum-journal-citation full-journal-citation\">J Bacteriol. 2017 Nov 14;199(24):e00476-17. doi: 10.1128\/JB.00476-17. Print 2017 Dec 15.<\/span><span class=\"citation-part\">PMID: <span class=\"docsum-pmid\">28924032<\/span><\/span><\/div>\n<div class=\"docsum-citation full-citation\"><a class=\"docsum-title\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26719219\/\" data-ga-category=\"result_click\" data-ga-action=\"3\" data-ga-label=\"26719219\" data-full-article-url=\"from_term=peter+t+buckley&amp;from_pos=3\" data-article-id=\"26719219\">Antibody-Based Biologics and Their Promise to Combat Staphylococcus aureus Infections. <\/a><span class=\"docsum-authors full-authors\">Sause WE, <b>Buckley PT<\/b>, Strohl WR, Lynch AS, Torres VJ.<\/span><span class=\"docsum-journal-citation full-journal-citation\">Trends Pharmacol Sci. 2016 Mar;37(3):231-241. doi: 10.1016\/j.tips.2015.11.008. Epub 2015 Dec 22.<\/span><span class=\"citation-part\">PMID: <span class=\"docsum-pmid\">26719219<\/span><\/span><\/div>\n<div class=\"docsum-citation full-citation\"><a class=\"docsum-title\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24412976\/\" data-ga-category=\"result_click\" data-ga-action=\"9\" data-ga-label=\"24412976\" data-full-article-url=\"from_term=peter+t+buckley&amp;from_pos=9\" data-article-id=\"24412976\">Transcriptome in vivo analysis (TIVA) of spatially defined single cells in live tissue. <\/a><span class=\"docsum-authors full-authors\">Lovatt D, Ruble BK, Lee J, Dueck H, Kim TK, Fisher S, Francis C, Spaethling JM, Wolf JA, Grady MS, Ulyanova AV, Yeldell SB, Griepenburg JC, <b>Buckley PT<\/b>, Kim J, Sul JY, Dmochowski IJ, Eberwine J.<\/span><span class=\"docsum-journal-citation full-journal-citation\">Nat Methods. 2014 Feb;11(2):190-6. doi: 10.1038\/nmeth.2804. Epub 2014 Jan 12.<\/span><span class=\"citation-part\">PMID: <span class=\"docsum-pmid\">24412976<\/span><\/span><\/div>\n<div class=\"docsum-citation full-citation\"><a class=\"docsum-title\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26719219\/\" data-ga-category=\"result_click\" data-ga-action=\"3\" data-ga-label=\"26719219\" data-full-article-url=\"from_term=peter+t+buckley&amp;from_pos=3\" data-article-id=\"26719219\">Antibody-Based Biologics and Their Promise to Combat Staphylococcus aureus Infections. <\/a><span class=\"docsum-authors full-authors\">Sause WE, <b>Buckley PT<\/b>, Strohl WR, Lynch AS, Torres VJ.<\/span><span class=\"docsum-journal-citation full-journal-citation\">Trends Pharmacol Sci. 2016 Mar;37(3):231-241. doi: 10.1016\/j.tips.2015.11.008. Epub 2015 Dec 22.<\/span><span class=\"citation-part\">PMID: <span class=\"docsum-pmid\">26719219<\/span><\/span><\/div>\n<div class=\"docsum-citation full-citation\"><a class=\"docsum-title\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24190870\/\" data-ga-category=\"result_click\" data-ga-action=\"4\" data-ga-label=\"24190870\" data-full-article-url=\"from_term=peter+t+buckley&amp;from_pos=4\" data-article-id=\"24190870\">Cytoplasmic intron retention, function, splicing, and the sentinel RNA hypothesis.<\/a> <span class=\"docsum-authors full-authors\"><b>Buckley PT<\/b>, Khaladkar M, Kim J, Eberwine J.<\/span><span class=\"docsum-journal-citation full-journal-citation\">Wiley Interdiscip Rev RNA. 2014 Mar-Apr;5(2):223-30. doi: 10.1002\/wrna.1203. Epub 2013 Nov 4.<\/span><span class=\"citation-part\">PMID: <span class=\"docsum-pmid\">24190870<\/span><\/span><\/div>\n<div class=\"docsum-citation full-citation\"><a class=\"docsum-title\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22032985\/\" data-ga-category=\"result_click\" data-ga-action=\"5\" data-ga-label=\"22032985\" data-full-article-url=\"from_term=peter+t+buckley&amp;from_pos=5\" data-article-id=\"22032985\">Drug targets: single-cell transcriptomics hastens unbiased discovery. <\/a><span class=\"docsum-authors full-authors\">Bartfai T, <b>Buckley PT<\/b>, Eberwine J.<\/span><span class=\"docsum-journal-citation full-journal-citation\">Trends Pharmacol Sci. 2012 Jan;33(1):9-16. doi: 10.1016\/j.tips.2011.09.006. Epub 2011 Oct 25.<\/span><span class=\"citation-part\">PMID: <span class=\"docsum-pmid\">22032985<\/span><\/span><\/div>\n<div class=\"docsum-citation full-citation\"><a class=\"docsum-title\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24192459\/\" data-ga-category=\"result_click\" data-ga-action=\"6\" data-ga-label=\"24192459\" data-full-article-url=\"from_term=peter+t+buckley&amp;from_pos=6\" data-article-id=\"24192459\">Serotonergic neuron regulation informed by in vivo single-cell transcriptomics. <\/a><span class=\"docsum-authors full-authors\">Spaethling JM, Piel D, Dueck H, <b>Buckley PT<\/b>, Morris JF, Fisher SA, Lee J, Sul JY, Kim J, Bartfai T, Beck SG, Eberwine JH.<\/span><span class=\"docsum-journal-citation full-journal-citation\">FASEB J. 2014 Feb;28(2):771-80. doi: 10.1096\/fj.13-240267. Epub 2013 Nov 5.<\/span><span class=\"citation-part\">PMID: <span class=\"docsum-pmid\">24192459<\/span><\/span><\/div>\n<div class=\"docsum-citation full-citation\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19855129?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&amp;ordinalpos=5\" target=\"_blank\" rel=\"noopener\">Melanocyte-like cells in the heart and pulmonary veins contribute to atrial arrhythmia triggers.<\/a> Levin MD, Lu MM, Petrenko NB, Hawkins BJ, Gupta TH, Lang D, Buckley PT, Jochems J, Liu F, Spurney CF, Yuan LJ, Jacobson JT, Brown CB, Huang L, Beermann F, Margulies KB, Madesh M, Eberwine JH, Epstein JA, Patel VV. &nbsp;J Clin Invest. 2009 Nov;119(11):3420-36. doi: 10.1172\/JCI39109. Epub 2009 Oct 12.<\/div>\n<div class=\"docsum-citation full-citation\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19846801?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&amp;ordinalpos=6\" target=\"_blank\" rel=\"noopener\">Insulin causes hyperthermia by direct inhibition of warm sensitive neurons.<\/a> Sanchez-Alavez M, Tabarean IV, Osborn O, Mitsukawa K, Schaefer J, Dubins J, Holmberg KH, Klein I, Klaus J, Gomez LF, Kolb H, Secrest J, Jochems J, Myashiro K, Buckley P, Hadcock JR, Eberwine J, Conti B, Bartfai T. &nbsp;Diabetes. 2009 Oct 21. [Epub ahead of print]<\/div>\n<div class=\"docsum-citation full-citation\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19650776?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&amp;ordinalpos=10\" target=\"_blank\" rel=\"noopener\">The reduced folate carrier (SLC19A1) c.80G&gt;A polymorphism is associated with red cell folate concentrations among women.<\/a> Stanis\u0142awska-Sachadyn A, Mitchell LE, Woodside JV, Buckley PT, Kealey C, Young IS, Scott JM, Murray L, Boreham CA, McNulty H, Strain JJ, Whitehead AS. &nbsp;Ann Hum Genet. 2009 Sep;73(Pt 5):484-91. Epub 2009 Jul 28.<\/div>\n<div class=\"docsum-citation full-citation\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19616944?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&amp;ordinalpos=12\" target=\"_blank\" rel=\"noopener\">Discovery of (3-endo)-3-(2-cyano-2,2-diphenylethyl)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane bromide as an efficacious inhaled muscarinic acetylcholine receptor antagonist for the treatment of COPD.<\/a> Wan Z, Laine DI, Yan H, Zhu C, Widdowson KL, Buckley PT, Burman M, Foley JJ, Sarau HM, Schmidt DB, Webb EF, Belmonte KE, Palovich M. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4560-2. Epub 2009 Jul 8.<\/div>\n<div class=\"docsum-citation full-citation\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19380745?ordinalpos=2&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">Transcriptome transfer produces a predictable cellular phenotype.<\/a> Sul JY, Wu CW, Zeng F, Jochems J, Lee MT, Kim TK, Peritz T, Buckley P, Cappelleri DJ, Maronski M, Kim M, Kumar V, Meaney D, Kim J, Eberwine J. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7624-9. Epub 2009 Apr 20.<\/div>\n<div class=\"docsum-citation full-citation\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18250327?ordinalpos=1&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">Cytoplasmic BK(Ca) channel intron-containing mRNAs contribute to the intrinsic excitability of hippocampal neurons.<\/a> Bell TJ, Miyashiro KY, Sul JY, McCullough R, Buckley PT, Jochems J, Meaney DF, Haydon P, Cantor C, Parsons TD, Eberwine J. &nbsp;Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1901-6. Epub 2008 Feb 4.<\/div>\n<div class=\"docsum-citation full-citation\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17911022?ordinalpos=26&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">Discovery of novel 8-azoniabicyclo[3.2.1]octane carbamates as muscarinic acetylcholine receptor antagonists.<\/a> Lain\u00e9 DI, Xie H, Buffet N, Foley JJ, Buckley P, Webb EF, Widdowson KL, Palovich MR, Belmonte KE. &nbsp;Bioorg Med Chem Lett. 2007 Nov 15;17(22):6066-9. Epub 2007 Sep 25.<\/div>\n<div class=\"docsum-citation full-citation\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16006193?ordinalpos=2&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">HIV-1 Viral protein-r (Vpr) protects against lethal superantigen challenge while maintaining homeostatic T cell levels in vivo.<\/a> Muthumani K, Choo AY, Hwang DS, Dayes NS, Chattergoon M, Mayilvahanan S, Thieu KP, Buckley PT, Emmanuel J, Premkumar A, Weiner DB. &nbsp;Mol Ther. 2005 Nov;12(5):910-21. Epub 2005 Jul 11.<\/div>\n<div class=\"docsum-citation full-citation\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15852036?ordinalpos=3&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">Nonpeptidic urotensin-II receptor antagonists I: in vitro pharmacological characterization of SB-706375.<\/a> Douglas SA, Behm DJ, Aiyar NV, Naselsky D, Disa J, Brooks DP, Ohlstein EH, Gleason JG, Sarau HM, Foley JJ, Buckley PT, Schmidt DB, Wixted WE, Widdowson K, Riley G, Jin J, Gallagher TF, Schmidt SJ, Ridgers L, Christmann LT, Keenan RM, Knight SD, Dhanak D. &nbsp;Br J Pharmacol. 2005 Jul;145(5):620-35.<\/div>\n<div class=\"docsum-citation full-citation\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15763543?ordinalpos=4&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">Cloning and pharmacological characterization of the cat urotensin-II receptor (UT).<\/a> Aiyar N, Johns DG, Ao Z, Disa J, Behm DJ, Foley JJ, Buckley PT, Sarau HM, van-der-Keyl HK, Elshourbagy NA, Douglas SA. &nbsp;Biochem Pharmacol. 2005 Apr 1;69(7):1069-79.<\/div>\n<div class=\"docsum-citation full-citation\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15512844?ordinalpos=92&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">BacMam recombinant baculoviruses in G protein-coupled receptor drug discovery.<\/a> Ames R, Fornwald J, Nuthulaganti P, Trill J, Foley J, Buckley P, Kost T, Wu Z, Romanos M. &nbsp;Receptors Channels. 2004;10(3-4):99-107. Review.<\/div>\n<div class=\"docsum-citation full-citation\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15475736?ordinalpos=5&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">A coding polymorphism in the CYSLT2 receptor with reduced affinity to LTD4 is associated with asthma.<\/a> Pillai SG, Cousens DJ, Barnes AA, Buckley PT, Chiano MN, Hosking LK, Cameron LA, Fling ME, Foley JJ, Green A, Sarau HM, Schmidt DB, Sprankle CS, Blumenthal MN, Vestbo J, Kennedy-Wilson K, Wixted WE, Wagner MJ, Anderson WH, Ignar DM; Investigators of the GAIN Network. &nbsp;Pharmacogenetics. 2004 Sep;14(9):627-33.<\/div>\n<div class=\"docsum-citation full-citation\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15292653?ordinalpos=6&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">Radioligand binding and functional characterization of recombinant human NmU1 and NmU2 receptors stably expressed in clonal human embryonic kidney-293 cells.<\/a> Aiyar N, Disa J, Foley JJ, Buckley PT, Wixted WE, Pullen M, Shabon U, Dul E, Szekeres PG, Elshourbagy NA, Sarau HM, Appelbaum E, Bolaky J. &nbsp;Pharmacology. 2004 Sep;72(1):33-41.<\/div>\n<div class=\"docsum-citation full-citation\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/14597565?ordinalpos=7&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">Regulation of TNF-alpha- and IFN-gamma-induced CXCL10 expression: participation of the airway smooth muscle in the pulmonary inflammatory response in chronic obstructive pulmonary disease.<\/a> Hardaker EL, Bacon AM, Carlson K, Roshak AK, Foley JJ, Schmidt DB, Buckley PT, Comegys M, Panettieri RA Jr, Sarau HM, Belmonte KE. &nbsp;FASEB J. 2004 Jan;18(1):191-3. Epub 2003 Nov 3.<\/div>\n<div class=\"docsum-citation full-citation\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12770925?ordinalpos=8&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">The neuromedin B receptor antagonist, BIM-23127, is a potent antagonist at human and rat urotensin-II receptors.<\/a> Herold CL, Behm DJ, Buckley PT, Foley JJ, Wixted WE, Sarau HM, Douglas SA. &nbsp;Br J Pharmacol. 2003 May;139(2):203-7.<\/div>\n<div class=\"docsum-citation full-citation\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12444152?ordinalpos=9&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">A potent and selective nonpeptide antagonist of CXCR2 inhibits acute and chronic models of arthritis in the rabbit.<\/a> Podolin PL, Bolognese BJ, Foley JJ, Schmidt DB, Buckley PT, Widdowson KL, Jin Q, White JR, Lee JM, Goodman RB, Hagen TR, Kajikawa O, Marshall LA, Hay DW, Sarau HM. &nbsp;J Immunol. 2002 Dec 1;169(11):6435-44.<\/div>\n<div class=\"docsum-citation full-citation\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11226387?ordinalpos=10&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">Molecular and pharmacological characterization of the murine tachykinin NK(3) receptor.<\/a> Sarau HM, Feild JA, Ames RS, Foley JJ, Nuthulaganti P, Schmidt DB, Buckley PT, Elshourbagy NA, Brawner ME, Luttmann MA, Giardina GA, Hay DW. &nbsp;Eur J Pharmacol. 2001 Feb 16;413(2-3):143-50.<\/div>\n<div class=\"docsum-citation full-citation\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/10953048?ordinalpos=11&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">Evidence that the proposed novel human &#8220;neurokinin-4&#8221; receptor is pharmacologically similar to the human neurokinin-3 receptor but is not of human origin.<\/a> Sarau HM, Mooney JL, Schmidt DB, Foley JJ, Buckley PT, Giardina GA, Wang DY, Lee JA, Hay DW. &nbsp;Mol Pharmacol. 2000 Sep;58(3):552-9.<\/div>\n<div class=\"docsum-citation full-citation\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/10851242?ordinalpos=12&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\">Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor.<\/a> Elshourbagy NA, Ames RS, Fitzgerald LR, Foley JJ, Chambers JK, Szekeres PG, Evans NA, Schmidt DB, Buckley PT, Dytko GM, Murdock PR, Milligan G, Groarke DA, Tan KB, Shabon U, Nuthulaganti P, Wang DY, Wilson S, Bergsma DJ, Sarau HM. &nbsp;J Biol Chem. 2000 Aug 25;275(34):25965-71.<\/div>\n<\/div>\n\n\n\n<h1 class=\"wp-block-heading\"><strong>Original Abstracts<\/strong><\/h1>\n\n\n\n<p>Buckley, P.T., Lee, M.,&nbsp;Sul, J.,&nbsp;Miyashiro, K.,&nbsp;Bell, T.,&nbsp;Fisher, S.,&nbsp;Kim, J.,&nbsp;Eberwine, J. &nbsp;Retention of specific intronic sequences is an important feature of post-transcriptional&nbsp;mRNA regulation in neuronal dendrites. <em>American Society for Cell Biology Annual Meeting, Dec 2009, San Diego, CA.<\/em><\/p>\n\n\n\n<p>Buckley, P.T., Lee, M., Bell, T.,&nbsp;Miyashiro, K., Sul, J.,&nbsp;Kim, J.,&nbsp;Eberwine, J. &nbsp;Single Cell mRNA Analysis: RNA drives Cellular Phenotype and Functionality of mRNA&nbsp;containing Retained Introns in Neurons. &nbsp;<em>American Society for Cell Biology Annual Meeting, Dec 2009, San Diego, CA.<\/em><\/p>\n\n\n\n<p>Bell, T.J.,&nbsp;Miyashiro, K.Y., Buckley, P.T., Eberwine, J. &nbsp;Splice variant-specific intron retention facilitates the structural diversity of BKCa&nbsp;channel mRNAs and proteins. &nbsp;<em>Society for Neuroscience Annual Meeting, Oct 2009, Chicago, IL.<\/em><\/p>\n\n\n\n<p>Francis, C.,&nbsp;Buckley, P.T., Fisher, S. A.,&nbsp;Lee, M. T.,&nbsp;Sul, J.-Y.,&nbsp;Gawlas, I., Guest, J., Eberwine, J. H., Kim, J.&nbsp;<strong><span style=\"font-weight: normal;\">Evolution of molecular physiology in mammalian neurons. &nbsp;<em>Society for Neuroscience Annual Meeting, Oct 2009, Chicago, IL.<\/em><\/span><\/strong><\/p>\n\n\n\n<p>Ross, J.R., Porter, B.E., Buckley, P.T., Eberwine, J. H., Robinson, M.B. &nbsp;Dramatic increases in dendritic targeting and mGluR-regulated translation of&nbsp;mRNA for the EAAC1 subtype of neuronal glutamate transporter after a seizure. <em>Society for Neuroscience Annual Meeting, Oct 2009, Chicago, IL.<\/em><\/p>\n\n\n\n<p>Bell, T.J.,&nbsp;Miyashiro, K.Y., Sul, J.-Y., Buckley, P.T., McCullough R., Cantor, C., Parsons, T.D., Eberwine, J. &nbsp;Structure, function, and regulation analysis of cytoplasmic intron-containing&nbsp;BKCa channel mRNAs in hippocampal neurons. <em>Society for Neuroscience Annual Meeting, Nov 2008, Washington, DC.<\/em><\/p>\n\n\n\n<p>Klein, I., Osborn, O., Tabarean, I., Sanchez-Alvarez, M., Gregorsson, E., Ross, B., Conti, B., Jochems, J., Buckley, P., Eberwine, J., Loging, W., Hadcock, J., Bartfai, T. &nbsp;Characterization of single warm sensitive hypothalamic neurons. <em>Society for Neuroscience Annual Meeting, Nov 2008, Washington, DC.<\/em><\/p>\n\n\n\n<p>Bell, T.J.,&nbsp;Miyashiro, K.Y., Sul, J., Buckley, P., Jochems, J., Parsons, T., Eberwine, J. &nbsp;Cytoplasmic BKCa channel intron-containing mRNAs contribute to the intrinsic excitability and BK&nbsp;channel protein distribution in hippocampal neurons. <em>Society for Neuroscience Annual Meeting, Nov 2007, San Diego, CA.<\/em><\/p>\n\n\n\n<p>Ross, J.R., Porter, B.E., Buckley, P.T., Eberwine, J. H., Robinson, M.B. &nbsp;The glutamate transporter, excitatory amino acid carrier 1 (EAAC1) mRNA is found in hippocampal&nbsp;dendrites and its translation may be locally controlled. <em>Society for Neuroscience Annual Meeting, Nov 2007, San Diego, CA.<\/em><\/p>\n\n\n\n<p><em><span style=\"font-style: normal;\">Wang, Y., Wang, F., Vinader, V.M., Hancock, A.P., Kerns, J.K., Morrow, D.M., Rao, P., Nguyen, C., Barrett, V.J., Browning, C., Hartmann, G., Andrew, D.P., Sarau, H.M., Foley, J.J., Schmidt, D.B., Buckley, P.T., Burman, M., Jurewicz, A.J., Fornwald, J.A., Wang, B., Moore, M.L., Rivero, R.A., Belmonte, K.E., Connor, H.E., &nbsp;Jin, J. &nbsp;Oxazolidinones as novel human CCR8 antagonists. <\/span>National Medicinal Chemistry Symposium, Jun 2006, Seattle, WA.<\/em><\/p>\n\n\n\n<p>Herold, C.L., Behm, D.J., Buckley, P.T.,&nbsp;Foley, J.J., Douglas, S.A. &nbsp;The peptidic somatostatin analogs lanreotide, BIM-23127, and BIM-23042 are urotensin-II receptor ligands. &nbsp;<em>Mid-Atlantic Pharmacology Society Annual Meeting, Sep 2002, Wilmington, DE.<\/em><\/p>\n\n\n\n<div id=\"_mcePaste\">Ames, R.S., Sarau, H.M., Chambers, J.K., Foley, J.J., Buckley, P.T., Schmidt, D.B., Tornetta, M., Rao, P., Levy, D., Slemmon, R., Wu, Z., King, A., Dally, J., LePage, C., Behm, D., Burns, M., Wilson, S., Muir, S., Szekeres, P.G., Evans, N., Fitzgerald, L., Dytko, G., Rice, K., Vawter, L., Gattu, N., Ellis, C.E., Lane, P., Tsui, P., Elshourgbagy, N.A., Shabon, U., Debouck, C., Bergsma, D.J. Orphan GPCR functional genomics: trials and tribulations of assay development. &nbsp;<em>MDC International Drug Discovery Conference, 2001, Lake Tahoe, NV.<\/em><\/div>\n\n\n\n<div id=\"_mcePaste\">Szekeres, P.G., Spinage, L., Butler, S., Smith, A., Muir, A., Middleton, S., Thompson, C., Ames, R.S., Sarau, H.M., Foley, J.J., Buckley, P.T., Rao, P., Chambers, J.K., Evans, N., Tornetta, M., Hill, J., Franks, A., McLaughlin, M., Guy, A., Elshourbagy, N.A., Shabon, U., Rice, K., Vawter, L., Gattu, N., &nbsp;Duckworth, M., Wilson, S., Bergsma, D.J. Deorphanization of human 7TM receptors using FLIPR success stories, pitfalls and potential solutions. &nbsp;<em>MDC International Drug Discovery Conference, 2001, Lake Tahoe, NV.<\/em><\/div>\n\n\n\n<div><em><span style=\"font-style: normal;\">Ames, R.S., Sarau, H.M., Chambers, J.K., Foley, J.J., Buckley, P.T., Schmidt, D.B., Tornetta, M., Rao, P., Levy, D., Slemmon, R., Wu, Z., King, A., Dally, J., LePage, C., Behm, D., Burns, M., Wilson, S., Muir, S., Szekeres, P.G., Evans, N., Fitzgerald, L., Dytko, G., Rice, K., Vawter, L., Gattu, N., Ellis, C.E., Lane, P., Tsui, P., Elshourgbagy, N.A., Shabon, U., Debouck, C., Bergsma, D.J. FLIPR: A platform for orphan G-protein coupled receptor functional genomics. &nbsp;<em>MDC International Drug Discovery Conference, 2000, Monterey, CA.<\/em><\/span><\/em><\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Key Peer Reviewed Journal Articles Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections.&nbsp;Buckley PT, Chan R, Fernandez J, Luo J, Lacey KA, DuMont AL, O&#8217;Malley A, Brezski RJ, Zheng S, Malia T, Whitaker B, Zwolak A, Payne A, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"class_list":["post-8","page","type-page","status-publish","hentry"],"jetpack_shortlink":"https:\/\/wp.me\/Pxni9-8","jetpack_sharing_enabled":true,"jetpack-related-posts":[],"_links":{"self":[{"href":"http:\/\/www.petertbuckley.com\/index.php?rest_route=\/wp\/v2\/pages\/8","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.petertbuckley.com\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/www.petertbuckley.com\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/www.petertbuckley.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.petertbuckley.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=8"}],"version-history":[{"count":9,"href":"http:\/\/www.petertbuckley.com\/index.php?rest_route=\/wp\/v2\/pages\/8\/revisions"}],"predecessor-version":[{"id":193,"href":"http:\/\/www.petertbuckley.com\/index.php?rest_route=\/wp\/v2\/pages\/8\/revisions\/193"}],"wp:attachment":[{"href":"http:\/\/www.petertbuckley.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=8"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}